New three-year data has been presented at the Alzheimer’s Association International Conference® 2024 (AAIC), showing the longer-term benefits of lecanemab treatment over three years without additional safety concerns. Alzheimer’s Society, the UK’s leading dementia charity, responds to the news: Dr Richard Oakley, Associate Director of Research and Innovation at Alzheimer's Society, said: “In recent clinical trials stemming from early work funded by Alzheimer’s Society 30 years ago, lecanemab has been shown to slow memory and thinking skills decline in people with early Alzheimer’s disease, by targeting a protein called amyloid. “This is the first study showing the longer-term benefits of lecanemab treatment over three years without additional safety concerns. This new research suggests people might need continuous treatment with lecanemab, but we need to see further data to confirm this. “This research also showed that the benefits of lecanemab treatment actually increase when it’s taken over three years. It’s encouraging that a small subgroup of participants in the very earliest stages of Alzheimer’s disease were found to have either no decline or an improvement in memory and thinking skills over this time frame – further supporting evidence that an early and accurate diagnosis is critical to maximising benefit from these drugs. “We’re still waiting to hear if lecanemab will be approved for use in the UK, but it has already been approved in the USA, China, Japan and South Korea.” “We’re at a turning point where people with Alzheimer’s disease could finally have treatments to slow its progression. But we know that currently people with dementia are not receiving an early or accurate enough diagnosis to access these treatments when they come, and a third of people with dementia in the UK don’t receive a diagnosis at all. “Alzheimer’s Society is urgently calling on the NHS to commit to plans for how they intend to improve early dementia diagnosis and deliver ground-breaking treatments when they are available, to the people who desperately need them.” -ENDS-
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